Ontology highlight
ABSTRACT:
SUBMITTER: Mao Y
PROVIDER: S-EPMC6960701 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Mao Yueyuan Y Xu Yediao Y Li Zhi Z Wang Yang Y Du Huanhuan H Liu Lei L Ding Ran R Liu Guodong G
Sensors (Basel, Switzerland) 20191204 24
Intracellular GSH is the most abundant non-protein biothiol and acts as a central antioxidant to defend against aging toxins and radicals. Meanwhile abnormal level of intracellular GSH concentration is directly related to some diseases. In this case, detecting intracellular GSH rapidly and sensitively is of great significance. We synthesize a simple fluorescent probe (named GP) which can discriminate GSH from Cys (cysteine) or Hcy (homocysteine) and presents a 50-fold fluorescence increasing. Th ...[more]