Ontology highlight
ABSTRACT:
SUBMITTER: BonDurant LD
PROVIDER: S-EPMC6964258 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Annual review of nutrition 20180504
Fibroblast growth factor 21 (FGF21) is an endocrine hormone derived from the liver that exerts pleiotropic effects on the body to maintain overall metabolic homeostasis. During the past decade, there has been an enormous effort made to understand the physiological roles of FGF21 in regulating metabolism and to identify the mechanism for its potent pharmacological effects to reverse diabetes and obesity. Through both human and rodent studies, it is now evident that FGF21 levels are dynamically re ...[more]