Genetic Determinants of Trehalose Utilization Are Not Associated With Severe Clostridium difficile Infection Outcome.
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ABSTRACT:
SUBMITTER: Saund K
PROVIDER: S-EPMC6966243 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
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Genetic Determinants of Trehalose Utilization Are Not Associated With Severe <i>Clostridium difficile</i> Infection Outcome.
Saund Katie K Rao Krishna K Young Vincent B VB Snitkin Evan S ES
Open forum infectious diseases 20200104 1
In a case-control study of patients with <i>Clostridium difficile</i> infection, we found no statistically significant association between the presence of trehalose utilization variants in infecting <i>C. difficile</i> strains and development of severe infection outcome. These results do not support trehalose utilization conferring enhanced virulence in the context of human <i>C. difficile</i> infections. ...[more]
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