Ontology highlight
ABSTRACT:
SUBMITTER: Quandt E
PROVIDER: S-EPMC6971155 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Cellular and molecular life sciences : CMLS 20190816 2
Regulation of cell division is orchestrated by cyclins, which bind and activate their catalytic workmates, the cyclin-dependent kinases (CDKs). Cyclins have been traditionally defined by an oscillating (cyclic) pattern of expression and by the presence of a characteristic "cyclin box" that determines binding to the CDKs. Noteworthy, the Human Genome Sequence Project unveiled the existence of several other proteins containing the "cyclin box" domain. These potential "cyclins" have been named new, ...[more]