Ontology highlight
ABSTRACT:
SUBMITTER: Quattrocelli M
PROVIDER: S-EPMC6975267 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Quattrocelli Mattia M Zelikovich Aaron S AS Jiang Zhen Z Peek Clara Bien CB Demonbreun Alexis R AR Kuntz Nancy L NL Barish Grant D GD Haldar Saptarsi M SM Bass Joseph J McNally Elizabeth M EM
JCI insight 20191219 24
In humans, chronic glucocorticoid use is associated with side effects like muscle wasting, obesity, and metabolic syndrome. Intermittent steroid dosing has been proposed in Duchenne Muscular Dystrophy patients to mitigate the side effects seen with daily steroid intake. We evaluated biomarkers from Duchenne Muscular Dystrophy patients, finding that, compared with chronic daily steroid use, weekend steroid use was associated with reduced serum insulin, free fatty acids, and branched chain amino a ...[more]