Ontology highlight
ABSTRACT:
SUBMITTER: Kirsebom F
PROVIDER: S-EPMC6981203 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Kirsebom Freja F Michalaki Christina C Agueda-Oyarzabal Marina M Johansson Cecilia C
Scientific reports 20200124 1
Lung and airway neutrophils are a hallmark of severe disease in infants with respiratory syncytial virus (RSV)-induced lower respiratory tract infections. Despite their abundance in the lungs during RSV infection of both mice and man, the role of neutrophils in viral control and in immune pathology is not clear. Here, antibody mediated neutrophil depletion was used to investigate the degree to which neutrophils impact the lung immune environment, the control of viral replication and the peak sev ...[more]