Ontology highlight
ABSTRACT:
SUBMITTER: Seko Y
PROVIDER: S-EPMC6981476 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Seko Yuya Y Yano Kohta K Takahashi Aya A Okishio Shinya S Kataoka Seita S Okuda Keiichiroh K Mizuno Naoki N Takemura Masashi M Taketani Hiroyoshi H Umemura Atsushi A Nishikawa Taichiro T Yamaguchi Kanji K Moriguchi Michihisa M Okanoue Takeshi T Itoh Yoshito Y
International journal of molecular sciences 20191225 1
Non-alcoholic fatty liver disease (NAFLD) is associated with chronic kidney disease (CKD). The aim of this retrospective study was to determine the risk factors for progression of CKD in patients with biopsy-proven NAFLD including patatin-like phospholipase domain containing 3 (PNPLA3) polymorphism. A total of 344 patients with biopsy-proven NAFLD were enrolled consecutively in this study. Multivariate analysis identified males (odds ratio (OR) 5.46), age (per 1 year, OR 1.07), and FIB-4 index ( ...[more]