Ontology highlight
ABSTRACT:
SUBMITTER: Maezawa M
PROVIDER: S-EPMC6983668 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Maezawa Masaki M Watanabe Ken-Ichi KI Horiuchi Noriyuki N Matsumoto Kotaro K Kobayashi Yoshiyasu Y Inokuma Hisashi H
The Journal of veterinary medical science 20191204 1
We performed a clonality analysis using polymerase chain reaction (PCR) for immunoglobulin heavy chain (IgH) gene rearrangement, specifically with regard to its utility as a method to diagnose bovine B-cell lymphoma. PCR for IgH gene rearrangement indicated monoclonal proliferation of B-cells in 24 of 35 cattle with B-cell lymphoma. In contrast, PCR for IgH gene rearrangement in lymph nodes and tumor tissues from 65 cattle diagnosed with tumors other than B-cell lymphoma and non-tumors revealed ...[more]