Ontology highlight
ABSTRACT:
SUBMITTER: Ledur PF
PROVIDER: S-EPMC6985105 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Ledur Pítia Flores PF Karmirian Karina K Pedrosa Carolina da Silva Gouveia CDSG Souza Leticia Rocha Quintino LRQ Assis-de-Lemos Gabriela G Martins Thiago Martino TM Ferreira Jéssica de Cassia Cavalheiro Gomes JCCG de Azevedo Reis Gabriel Ferreira GF Silva Eduardo Santos ES Silva Débora D Salerno José Alexandre JA Ornelas Isis Moraes IM Devalle Sylvie S Madeiro da Costa Rodrigo Furtado RF Goto-Silva Livia L Higa Luiza Mendonça LM Melo Adriana A Tanuri Amilcar A Chimelli Leila L Murata Marcos Massao MM Garcez Patrícia Pestana PP Filippi-Chiela Eduardo Cremonese EC Galina Antonio A Borges Helena Lobo HL Rehen Stevens Kastrup SK
Scientific reports 20200127 1
Zika virus (ZIKV) has been extensively studied since it was linked to congenital malformations, and recent research has revealed that astrocytes are targets of ZIKV. However, the consequences of ZIKV infection, especially to this cell type, remain largely unknown, particularly considering integrative studies aiming to understand the crosstalk among key cellular mechanisms and fates involved in the neurotoxicity of the virus. Here, the consequences of ZIKV infection in iPSC-derived astrocytes are ...[more]