Ontology highlight
ABSTRACT:
SUBMITTER: Allegrini AG
PROVIDER: S-EPMC6986352 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Allegrini A G AG Selzam S S Rimfeld K K von Stumm S S Pingault J B JB Plomin R R
Molecular psychiatry 20190411 6
Recent advances in genomics are producing powerful DNA predictors of complex traits, especially cognitive abilities. Here, we leveraged summary statistics from the most recent genome-wide association studies of intelligence and educational attainment, with highly genetically correlated traits, to build prediction models of general cognitive ability and educational achievement. To this end, we compared the performances of multi-trait genomic and polygenic scoring methods. In a representative UK s ...[more]