Dataset Information

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children's Study.

ABSTRACT: OBJECTIVE:For several observational studies that have reported the factors related to gastroschisis, the target population in these studies was mainly residents of Europe or the US, and there is little data on the Asian population. In this study, we summarised characteristics of Japanese women who delivered infants with gastroschisis, particularly focusing on the pre-pregnancy body mass index (BMI), which was found to be inversely associated with gastroschisis in past studies, because the distribution of BMI is clearly different in Asia and the West. RESULTS:We used data from a nationwide birth cohort study which recruited pregnant women between 2011 and 2014. Among 92,796 women who delivered singleton live births, the frequency of underweight (pre-pregnancy BMI?

SUBMITTER: Michikawa T

PROVIDER: S-EPMC6990474 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children's Study.

Michikawa Takehiro T Yamazaki Shin S Suda Eiko E Kuroda Tatsuo T Nakayama Shoji F SF Isobe Tomohiko T Kobayashi Yayoi Y Iwai-Shimada Miyuki M Sekiyama Makiko M Kawamoto Toshihiro T Nitta Hiroshi H

BMC research notes 20200130 1

<h4>Objective</h4>For several observational studies that have reported the factors related to gastroschisis, the target population in these studies was mainly residents of Europe or the US, and there is little data on the Asian population. In this study, we summarised characteristics of Japanese women who delivered infants with gastroschisis, particularly focusing on the pre-pregnancy body mass index (BMI), which was found to be inversely associated with gastroschisis in past studies, because th ...[more]

PMID: 32000843

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Project description:BackgroundPersistent pain during pregnancy is a significant health issue, which could be correlated with psychological distress resulting from inadequate social support. This study aims to investigate whether the relationship between poor social support and antenatal pain is mediated by psychological distress. We also aimed to examine whether social cohesion moderates the influence of psychological distress on the relationship between social support and antenatal pain.MethodsWe analysed 94,517 pregnancies of women from a Japanese national birth cohort completed questionnaires assessing pain, psychological distress, social support and social cohesion. Psychological distress was assessed using the Kessler Psychological Distress Scale. Two types of models were used: the mediation model to examine whether the association between social support and pain was mediated by psychological distress; the moderated mediation model to analyse whether social cohesion buffered the negative effect of inadequate social support on pain. Demographic, socioeconomic and psychological factors were controlled for in all analyses.ResultsPsychological distress was fully mediated the association between social support and pain. Social cohesion had a focal moderation effect on the inverse association between social support and psychological distress (unstandardized regression coefficient [β] = 0.09; 95% CI, 0.07-0.11) and functioned as moderator for the indirect effect of social support on antenatal pain (index of moderated mediation = 0.006; 95% CI, 0.004-0.007).ConclusionsPoor social support was related to antenatal pain through psychological distress, possibly buffered by social cohesion. During the antenatal period, social support and cohesion are important for women.SignificanceIn this study, poor social support was found to be associated with pain intensity during pregnancy, which was mediated by psychological distress and might be buffered by desirable social cohesion. This finding could potentially help healthcare providers and policy makers to understand the importance of desirable social cohesion in preventing pain among pregnant women.

Dataset Information

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children's Study.

Publications

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children's Study.

Similar Datasets

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