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Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays.

ABSTRACT: Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to implement chemical signaling in GUV colonies and protocell/living cell consortia. The methodology offers an alternative approach to GUV micro-array fabrication and provides new opportunities in protocell research and bottom-up synthetic biology.

SUBMITTER: Wang X

PROVIDER: S-EPMC6991169 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays.

Wang Xuejing X Tian Liangfei L Du Hang H Li Mei M Mu Wei W Drinkwater Bruce W BW Han Xiaojun X Mann Stephen S

Chemical science 20190918 41

Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to implement chemical signaling in GUV colonies and protocell/living cell consortia. The methodology offers an alternative approach to GUV micro-array fabrication and provides new opportunities in protocell research and bottom-up synthetic biology. ...[more]

PMID: 32055320

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