Molecular imaging biomarkers for immune checkpoint inhibitor therapy.
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ABSTRACT:
SUBMITTER: van de Donk PP
PROVIDER: S-EPMC6993216 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Molecular imaging biomarkers for immune checkpoint inhibitor therapy.
van de Donk Pim P PP Kist de Ruijter Laura L Lub-de Hooge Marjolijn N MN Brouwers Adrienne H AH van der Wekken Anthonie J AJ Oosting Sjoukje F SF Fehrmann Rudolf Sn RS de Groot Derk Jan A DJA de Vries Elisabeth Ge EG
Theranostics 20200101 4
Immune checkpoint inhibitors (ICIs) have substantially changed the field of oncology over the past few years. ICIs offer an alternative treatment strategy by exploiting the patients' immune system, resulting in a T cell mediated anti-tumor response. These therapies are effective in multiple different tumor types. Unfortunately, a substantial group of patients do not respond to ICIs. Molecular imaging, using single-photon emission computed tomography (SPECT) and positron emission tomography (PET) ...[more]
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