Ontology highlight
ABSTRACT:
SUBMITTER: Yang C
PROVIDER: S-EPMC6996576 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
The EMBO journal 20190926 3
Meiosis is key to sexual reproduction and genetic diversity. Here, we show that the Arabidopsis cyclin-dependent kinase Cdk1/Cdk2 homolog CDKA;1 is an important regulator of meiosis needed for several aspects of meiosis such as chromosome synapsis. We identify the chromosome axis protein ASYNAPTIC 1 (ASY1), the Arabidopsis homolog of Hop1 (homolog pairing 1), essential for synaptonemal complex formation, as a target of CDKA;1. The phosphorylation of ASY1 is required for its recruitment to the ch ...[more]