Ontology highlight
ABSTRACT:
SUBMITTER: Fariyike B
PROVIDER: S-EPMC6998035 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Mechanisms of ageing and development 20181207
MicroRNA's are small non-coding RNAs that regulate the expression of genes by targeting the 3' UTR's of mRNA. Studies reveal that miRNAs play a pivotal role in normal musculoskeletal function such as mesenchymal stem cell differentiation, survivability and apoptosis, osteogenesis, and chondrogenesis. Changes in normal miRNA expression have been linked to a number of pathological disease processes. Additionally, with aging, it is noted that there is dysregulation in the normal function of stem ce ...[more]