Ontology highlight
ABSTRACT:
SUBMITTER: Huraib GB
PROVIDER: S-EPMC7003175 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Huraib Ghaleb Bin GB Al Harthi Fahad F Arfin Misbahul M Aljamal Abdulrahman A Alrawi Abdulqader Saeed AS Al-Asmari Abdulrahman A
Biomarker insights 20200131
The <i>protein tyrosine phosphatase nonreceptor 22 (PTPN22)</i> is associated with susceptibility to autoimmune diseases. The functional polymorphism in <i>PTPN22</i> at 1857 is a strong risk factor for vitiligo susceptibility in Europeans; however, controversy exits in other populations. Present study was aimed to determine whether the PTPN22 C1857T polymorphism confers susceptibility to vitiligo in Saudi Arabians. Genomic DNA was extracted and amplified using tetra primer amplification-refract ...[more]