Ontology highlight
ABSTRACT:
SUBMITTER: Iali W
PROVIDER: S-EPMC7004201 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Iali Wissam W Roy Soumya S SS Tickner Ben J BJ Ahwal Fadi F Kennerley Aneurin J AJ Duckett Simon B SB
Angewandte Chemie (International ed. in English) 20190617 30
Hyperpolarisation methods that premagnetise agents such as pyruvate are currently receiving significant attention because they produce sensitivity gains that allow disease tracking and interrogation of cellular metabolism by magnetic resonance. Here, we communicate how signal amplification by reversible exchange (SABRE) can provide strong <sup>13</sup> C pyruvate signal enhancements in seconds through the formation of the novel polarisation transfer catalyst [Ir(H)<sub>2</sub> (η<sup>2</sup> -py ...[more]