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Assessment of the anterior segment of patients with primary congenital glaucoma using handheld optical coherence tomography.


ABSTRACT:

Purpose

To investigate the potential of handheld optical coherence tomography (HH-OCT) in assessing the anterior segment of the eye in patients with primary congenital glaucoma.

Design

A prospective, case-controlled observational study.

Participants

Twenty-two patients with primary congenital glaucoma (PCG, 9 females and 13 males; mean age 4.36?±?3.4 years) and age-, gender- and ethnicity-matched healthy participants.

Methods

Anterior OCT was performed in all participants using a high-resolution HH SD-OCT device (Envisu 2300, Leica Microsystems, Germany) without anaesthesia or sedation.

Results

Anterior HH-OCT in PCG visualised Haab's striae in 14.3%, uneven internal cornea in 9.5% and epithelial thickening in 11.9% of patients with central corneal thickening (CCT, p?ConclusionsAnterior HH-OCT has significant potential to improve diagnosis and management of PCG. Clinically relevant information can be obtained non-invasively and without sedation. High specificity makes anterior HH-OCT an important adjunct for management of PCG. Excellent visualisation of the iris insertion on OCT indicates potential for AS OCT to assist with surgical planning, including decision on the type of surgery and location of the incision.

SUBMITTER: Pilat AV 

PROVIDER: S-EPMC7005739 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Publications

Assessment of the anterior segment of patients with primary congenital glaucoma using handheld optical coherence tomography.

Pilat Anastasia V AV   Proudlock Frank A FA   Shah Sonal S   Sheth Viral V   Purohit Ravi R   Abbot Joseph J   Gottlob Irene I  

Eye (London, England) 20190318 8


<h4>Purpose</h4>To investigate the potential of handheld optical coherence tomography (HH-OCT) in assessing the anterior segment of the eye in patients with primary congenital glaucoma.<h4>Design</h4>A prospective, case-controlled observational study.<h4>Participants</h4>Twenty-two patients with primary congenital glaucoma (PCG, 9 females and 13 males; mean age 4.36 ± 3.4 years) and age-, gender- and ethnicity-matched healthy participants.<h4>Methods</h4>Anterior OCT was performed in all partici  ...[more]

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