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ABSTRACT: Purpose
To investigate the potential of handheld optical coherence tomography (HH-OCT) in assessing the anterior segment of the eye in patients with primary congenital glaucoma.Design
A prospective, case-controlled observational study.Participants
Twenty-two patients with primary congenital glaucoma (PCG, 9 females and 13 males; mean age 4.36?±?3.4 years) and age-, gender- and ethnicity-matched healthy participants.Methods
Anterior OCT was performed in all participants using a high-resolution HH SD-OCT device (Envisu 2300, Leica Microsystems, Germany) without anaesthesia or sedation.Results
Anterior HH-OCT in PCG visualised Haab's striae in 14.3%, uneven internal cornea in 9.5% and epithelial thickening in 11.9% of patients with central corneal thickening (CCT, p?ConclusionsAnterior HH-OCT has significant potential to improve diagnosis and management of PCG. Clinically relevant information can be obtained non-invasively and without sedation. High specificity makes anterior HH-OCT an important adjunct for management of PCG. Excellent visualisation of the iris insertion on OCT indicates potential for AS OCT to assist with surgical planning, including decision on the type of surgery and location of the incision.
SUBMITTER: Pilat AV
PROVIDER: S-EPMC7005739 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Pilat Anastasia V AV Proudlock Frank A FA Shah Sonal S Sheth Viral V Purohit Ravi R Abbot Joseph J Gottlob Irene I
Eye (London, England) 20190318 8
<h4>Purpose</h4>To investigate the potential of handheld optical coherence tomography (HH-OCT) in assessing the anterior segment of the eye in patients with primary congenital glaucoma.<h4>Design</h4>A prospective, case-controlled observational study.<h4>Participants</h4>Twenty-two patients with primary congenital glaucoma (PCG, 9 females and 13 males; mean age 4.36 ± 3.4 years) and age-, gender- and ethnicity-matched healthy participants.<h4>Methods</h4>Anterior OCT was performed in all partici ...[more]