Ontology highlight
ABSTRACT:
SUBMITTER: Montero-Herradon S
PROVIDER: S-EPMC7009794 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Organogenesis 20171001 4
EphB and their ligands ephrin-B are an important family of protein tyrosine kinase receptors involved in thymocyte-thymic epithelial cell interactions known to be key for the maturation of both thymic cell components. In the present study, we have analyzed the maturation of cortical thymic epithelium in EphB-deficient thymuses evaluating the relative relevance of EphB2 and EphB3 in the process. Results support a relationship between the epithelial hypocellularity of mutant thymuses and altered d ...[more]