New technologies to analyse protein function: an intrinsic disorder perspective.
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ABSTRACT:
SUBMITTER: Uversky VN
PROVIDER: S-EPMC7014577 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
New technologies to analyse protein function: an intrinsic disorder perspective.
F1000Research 20200210
Functions of intrinsically disordered proteins do not require structure. Such structure-independent functionality has melted away the classic rigid "lock and key" representation of structure-function relationships in proteins, opening a new page in protein science, where molten keys operate on melted locks and where conformational flexibility and intrinsic disorder, structural plasticity and extreme malleability, multifunctionality and binding promiscuity represent a new-fangled reality. Analysi ...[more]
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