Ontology highlight
ABSTRACT:
SUBMITTER: Dykeman EC
PROVIDER: S-EPMC7015319 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
PLoS computational biology 20200212 2
Computational modelling of in vivo protein synthesis is highly complicated, as it requires the simulation of ribosomal movement over the entire transcriptome, as well as consideration of the concentration effects from 40+ different types of tRNAs and numerous other protein factors. Here I report on the development of a stochastic model for protein translation that is capable of simulating the dynamical process of in vivo protein synthesis in a prokaryotic cell containing several thousand unique ...[more]