Ontology highlight
ABSTRACT:
SUBMITTER: Han Y
PROVIDER: S-EPMC7015429 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
PLoS computational biology 20200131 1
For a genetically identical microbial population, multi-gene expression in various environments requires effective allocation of limited resources and precise control of heterogeneity among individual cells. However, it is unclear how resource allocation and cell-to-cell variation jointly shape the overall performance. Here we demonstrate a Simpson's paradox during overexpression of multiple genes: two competing proteins in single cells correlated positively for every induction condition, but th ...[more]