Ontology highlight
ABSTRACT:
SUBMITTER: Yang SNY
PROVIDER: S-EPMC7016805 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Yang Sundy N Y SNY Atkinson Sarah C SC Audsley Michelle D MD Heaton Steven M SM Jans David A DA Borg Natalie A NA
Cells 20200109 1
Viral disease is one of the greatest burdens for human health worldwide, with an urgent need for efficacious antiviral strategies. While antiviral drugs are available, in many cases, they are prone to the development of drug resistance. A way to overcome drug resistance associated with common antiviral therapies is to develop antivirals targeting host cellular co-factors critical to viral replication, such as DEAD-box helicase 3 X-linked (DDX3X), which plays key roles in RNA metabolism and the a ...[more]