Ontology highlight
ABSTRACT:
SUBMITTER: Prusinkiewicz MA
PROVIDER: S-EPMC7017314 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Prusinkiewicz Martin A MA Gameiro Steven F SF Ghasemi Farhad F Dodge Mackenzie J MJ Zeng Peter Y F PYF Maekebay Hanna H Barrett John W JW Nichols Anthony C AC Mymryk Joe S JS
Cancers 20200120 1
Human papillomavirus (HPV) causes an increasing number of head and neck squamous cell carcinomas (HNSCCs). Altered metabolism contributes to patient prognosis, but the impact of HPV status on HNSCC metabolism remains relatively uncharacterized. We hypothesize that metabolism-related gene expression differences unique to HPV-positive HNSCC influences patient survival. The Cancer Genome Atlas RNA-seq data from primary HNSCC patient samples were categorized as 73 HPV-positive, 442 HPV-negative, and ...[more]