Ontology highlight
ABSTRACT:
SUBMITTER: Ekanayake Weeramange C
PROVIDER: S-EPMC7348958 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Ekanayake Weeramange Chameera C Tang Kai Dun KD Vasani Sarju S Langton-Lockton Julian J Kenny Liz L Punyadeera Chamindie C
Cells 20200531 6
Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also reveals alterations in its methylation profile. The intrinsic ability of HPV oncoproteins E6 and E7 to interfere with DNA methyltransferase activity contributes to these methylation changes. There are many genes that have been reported to be differentially methylated in HPV-driven HNC. Some of these genes are involved in major ...[more]