Ontology highlight
ABSTRACT:
SUBMITTER: Batyrev D
PROVIDER: S-EPMC7017363 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Batyrev Daniel D Lapid Elisheva E Carmel Liran L Meshorer Eran E
Cells 20191224 1
High coverage sequences of archaic humans enabled the reconstruction of their DNA methylation patterns. This allowed comparing gene regulation between human groups, and linking such regulatory changes to phenotypic differences. In a previous work, a detailed comparison of DNA methylation in modern humans, archaic humans, and chimpanzees revealed 873 modern human-derived differentially methylated regions (DMRs). To understand the regulatory implications of these DMRs, we defined differentially me ...[more]