Ontology highlight
ABSTRACT:
SUBMITTER: Lustgarten MS
PROVIDER: S-EPMC7019845 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Nutrients 20191230 1
Decreased renal function, elevated circulating levels of urea, intestinal levels of urea-degrading bacteria, and gut-derived uremic metabolites are present in end-stage renal disease (ESRD), a cohort that has reduced muscle mass and physical function, and poor muscle composition. This phenotype, defined as the kidney-gut-muscle axis, is similarly represented in older adults that do not have ESRD. The purpose of this short communication is to illuminate these findings, and to propose a strategy t ...[more]