Ontology highlight
ABSTRACT:
SUBMITTER: Vansant G
PROVIDER: S-EPMC7019976 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Vansant Gerlinde G Bruggemans Anne A Janssens Julie J Debyser Zeger Z
Viruses 20200110 1
Today HIV infection cannot be cured due to the presence of a reservoir of latently infected cells inducing a viral rebound upon treatment interruption. Hence, the latent reservoir is considered as the major barrier for an HIV cure. So far, efforts to completely eradicate the reservoir via a shock-and-kill approach have proven difficult and unsuccessful. Therefore, more research has been done recently on an alternative block-and-lock functional cure strategy. In contrast to the shock-and-kill str ...[more]