Ontology highlight
ABSTRACT:
SUBMITTER: Ali MK
PROVIDER: S-EPMC7020884 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Ali Md Kaisar MK Zhen Gong G Nzungize Lambert L Stojkoska Andrea A Duan Xiangke X Li Chunyan C Duan Wei W Xu Junqi J Xie Jianping J
Frontiers in cellular and infection microbiology 20200207
The <i>Mycobacterium (M.) tuberculosis</i> comprising proline-glutamic acid (PE) subfamily proteins associate with virulence, pathogenesis, and host-immune modulations. While the functions of most of this family members are not yet explored. Here, we explore the functions of "PE only" subfamily member PE31 (Rv3477) in virulence and host-pathogen interactions. We have expressed the <i>M. tuberculosis</i> PE31 in non-pathogenic <i>Mycobacterium smegmatis</i> strain (Ms_PE31) and demonstrated that ...[more]