Ontology highlight
ABSTRACT:
SUBMITTER: Sarwar MS
PROVIDER: S-EPMC7023344 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Biomolecules 20200116 1
Since the first discovery in 1961, more than 1300 <i>ent</i>-kaurane diterpenoids have been isolated and identified from different plant sources, mainly the genus <i>Isodon</i>. Chemically, they consist of a perhydrophenanthrene subunit and a cyclopentane ring. A large number of reports describe the anticancer potential and mechanism of action of <i>ent</i>-kaurane compounds in a series of cancer cell lines. Oridonin is one of the prime anticancer <i>ent</i>-kaurane diterpenoids that is currentl ...[more]