Ontology highlight
ABSTRACT:
SUBMITTER: Gao J
PROVIDER: S-EPMC7025113 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Mediators of inflammation 20200205
Chemokine C-X-C ligand 10 (CXCL10), also known as interferon-<i>γ</i>-inducible protein 10 (IP-10), exerts biological function mainly through binding to its specific receptor, CXCR3. Studies have shown that renal resident mesangial cells, renal tubular epithelial cells, podocytes, endothelial cells, and infiltrating inflammatory cells express CXCL10 and CXCR3 under inflammatory conditions. In the last few years, strong experimental and clinical evidence has indicated that CXCL10 is involved in t ...[more]