Ontology highlight
ABSTRACT:
SUBMITTER: Aranda-Diaz A
PROVIDER: S-EPMC7025823 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Aranda-Díaz Andrés A Obadia Benjamin B Dodge Ren R Thomsen Tani T Hallberg Zachary F ZF Güvener Zehra Tüzün ZT Ludington William B WB Huang Kerwyn Casey KC
eLife 20200129
Predicting antibiotic efficacy within microbial communities remains highly challenging. Interspecies interactions can impact antibiotic activity through many mechanisms, including alterations to bacterial physiology. Here, we studied synthetic communities constructed from the core members of the fruit fly gut microbiota. Co-culturing of <i>Lactobacillus plantarum</i> with <i>Acetobacter</i> species altered its tolerance to the transcriptional inhibitor rifampin. By measuring key metabolites and ...[more]