Ontology highlight
ABSTRACT:
SUBMITTER: Xu Z
PROVIDER: S-EPMC7026085 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Xu Zhi Z Xie Chunming C Xia Lu L Yuan Yonggui Y Zhu Hong H Huang Xiaofa X Li Caihua C Tao Yu Y Qu Xiaoxiao X Zhang Fengyu F Zhang Zhijun Z
Translational psychiatry 20200123 1
In order to determine the role of single nucleotide variants (SNVs) in modulating antidepressant response, we conducted a study, consisting of 929 major depressive disorder (MDD) patients, who were treated with antidepressant drugs (drug-only) or in combination with a repetitive transcranial magnetic stimulation (plus-rTMS), followed by targeted exome sequencing analysis. We found that the "plus-rTMS" patients presented a more effective response to the treatment when compared to the 'drug-only' ...[more]