Preclinical Models of Malignant Mesothelioma.
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ABSTRACT:
SUBMITTER: Testa JR
PROVIDER: S-EPMC7026500 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Preclinical Models of Malignant Mesothelioma.
Testa Joseph R JR Berns Anton A
Frontiers in oncology 20200211
Rodent models of malignant mesothelioma help facilitate the understanding of the biology of this highly lethal cancer and to develop and test new interventions. Introducing the same genetic lesions as found in human mesothelioma in mice results in tumors that show close resemblance with the human disease counterpart. This includes the extensive inflammatory responses that characterize human malignant mesothelioma. The relatively fast development of mesothelioma in mice when the appropriate combi ...[more]
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