Ontology highlight
ABSTRACT:
SUBMITTER: Meng W
PROVIDER: S-EPMC7028719 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Meng Weihua W Adams Mark J MJ Reel Parminder P Rajendrakumar Aravind A Huang Yu Y Deary Ian J IJ Palmer Colin N A CNA McIntosh Andrew M AM Smith Blair H BH
European journal of human genetics : EJHG 20191029 3
Correlations between pain phenotypes and psychiatric traits such as depression and the personality trait of neuroticism are not fully understood. In this study, we estimated the genetic correlations of eight pain phenotypes (defined by the UK Biobank, n = 151,922-226,683) with depressive symptoms, major depressive disorders and neuroticism using the the cross-trait linkage disequilibrium score regression (LDSC) method integrated in the LD Hub. We also used the LDSC software to calculate the gene ...[more]