Ontology highlight
ABSTRACT:
SUBMITTER: Devkota P
PROVIDER: S-EPMC7031241 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Devkota Prajwal P Wuchty Stefan S
Scientific reports 20200219 1
Inputs to molecular pathways that are the backbone of cellular activity drive the cell to certain outcomes and phenotypes. Here, we investigated proteins that topologically controlled different human pathways represented as independent molecular interaction networks, suggesting that a minority of proteins control a high number of pathways and vice versa. Transcending different topological levels, proteins that controlled a large number of pathways also controlled a network of interactions when a ...[more]