Ontology highlight
ABSTRACT:
SUBMITTER: E Silva RF
PROVIDER: S-EPMC7033680 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
E Silva Rafael de Freitas RF de Oliveira Beatriz Coutinho BC da Silva Ailton Alvaro AA Brelaz de Castro Maria Carolina Accioly MCA Ferreira Luiz Felipe Gomes Rebello LFGR Hernandes Marcelo Zaldini MZ de Brito Maria Edileuza Felinto MEF de-Melo-Neto Osvaldo Pompílio OP Rezende Antônio Mauro AM Pereira Valéria Rêgo Alves VRA
Frontiers in immunology 20200214
<b>Background:</b> A safe and effective vaccine against human leishmaniasis still requires the identification of better antigens for immunization and adequate models to evaluate the immune response. To support vaccine development, this work tested the immunogenicity of 10 different peptides derived from the proteome of <i>Leishmania braziliensis</i>, which were selected by their <i>in silico</i> affinity to MHC complexes. <b>Research design and Methods:</b> Comparative cell proliferation assays ...[more]