Ontology highlight
ABSTRACT:
SUBMITTER: Lavin TK
PROVIDER: S-EPMC7033752 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Lavin Thomas K TK Jin Lei L Lea Nicholas E NE Wickersham Ian R IR
Frontiers in synaptic neuroscience 20200214
Monosynaptically-restricted transsynaptic tracing using deletion-mutant rabies virus (RV) has become a widely used technique in neuroscience, allowing identification, imaging, and manipulation of neurons directly presynaptic to a starting neuronal population. Its most common implementation is to use Cre mouse lines in combination with Cre-dependent "helper" adeno-associated viral vectors (AAVs) to supply the required genes to the targeted population before subsequent injection of a first-generat ...[more]