Ontology highlight
ABSTRACT:
SUBMITTER: Du B
PROVIDER: S-EPMC7033910 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Du Bujie B Jiang Xingya X Huang Yingyu Y Li Siqing S Lin Jason C JC Yu Mengxiao M Zheng Jie J
Bioconjugate chemistry 20191123 2
Subtle changes in size can induce distinct responses of the body to hard nanomaterials; however, it is largely unknown whether just a few ethylene oxide unit differences in soft poly(ethylene glycol) (PEG) molecules could significantly alter the renal clearance of small molecules. By systematically investigating in vivo transport of the representative renal clearable organic dyes, IRDye800CW after being conjugated with a series of PEG molecules with molecular weight (MW) below 10 kDa, we found a ...[more]