Ontology highlight
ABSTRACT:
SUBMITTER: Schneider SA
PROVIDER: S-EPMC7035220 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Schneider Susanne A SA Alcalay Roy N RN
Journal of neurology 20200123 3
In recent years, numerous clinical trials for disease modification in Parkinson's disease (PD) have failed, possibly because of a "one-size-fits all" approach. Alternatively, a precision medicine approach, which customises treatments based on patients' individual genotype, may help reach disease modification. Here, we review clinical trials that target genetic forms of PD, i.e., GBA-associated and LRRK2-associated PD. In summary, six ongoing studies which explicitely recruit GBA-PD patients, and ...[more]