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Available and emerging treatments for Parkinson's disease: a review.

ABSTRACT: Parkinson's disease is a commonly encountered neurodegenerative disorder primarily found in aged populations. A number of medications are available to control symptoms, although these are less effective in advanced disease. Deep brain stimulation provides a practicable alternative at this stage, although a minority of patients meet the strict criteria for surgery. Novel medications that provide enhanced symptomatic control remain in developmental demand. Both gene and cell-based therapies have shown promise in early clinical studies. A major unmet need is a treatment that slows or stops disease progression.

SUBMITTER: Hickey P

PROVIDER: S-EPMC3096539 | biostudies-other | 2011

REPOSITORIES: biostudies-other

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Available and emerging treatments for Parkinson's disease: a review.

Hickey Patrick P Stacy Mark M

Drug design, development and therapy 20110502

Parkinson's disease is a commonly encountered neurodegenerative disorder primarily found in aged populations. A number of medications are available to control symptoms, although these are less effective in advanced disease. Deep brain stimulation provides a practicable alternative at this stage, although a minority of patients meet the strict criteria for surgery. Novel medications that provide enhanced symptomatic control remain in developmental demand. Both gene and cell-based therapies have s ...[more]

PMID: 21607020

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