Neuroprem: the Neuro-developmental outcome of very low birth weight infants in an Italian region.

ABSTRACT: INTRODUCTION:The survival of preterm babies has increased worldwide, but the risk of neuro-developmental disabilities remains high, which is of concern to both the public and professionals. The early identification of children at risk of neuro-developmental disabilities may increase access to intervention, potentially influencing the outcome. AIMS:Neuroprem is an area-based prospective cohort study on the neuro-developmental outcome of very low birth weight (VLBW) infants that aims to define severe functional disability at 2?years of age. METHODS:Surviving VLBW infants from an Italian network of 7 neonatal intensive care units (NICUs) were assessed for 24?months through the Griffiths Mental Developmental Scales (GMDS-R) or the Bayley Scales of Infant and Toddler Development (BSDI III) and neuro-functional evaluation according to the International Classification of Disability and Health (ICF-CY). The primary outcome measure was severe functional disability at 2?years of age, defined as cerebral palsy, a BSDI III cognitive composite score?

SUBMITTER: Lugli L 

PROVIDER: S-EPMC7036238 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature