Ontology highlight
ABSTRACT:
SUBMITTER: Bavli Y
PROVIDER: S-EPMC7037198 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Bavli Yaelle Y Chen Bing-Mae BM Roffler Steve R SR Dobrovolskaia Marina A MA Elnekave Eldad E Ash Shifra S Barenholz Yechezkel Y Turjeman Keren K
Molecules (Basel, Switzerland) 20200128 3
PEGylated nanomedicines are known to induce infusion reactions (IRs) that in some cases can be life-threatening. Herein, we report a case study in which a patient with rare mediastinal and intracardiac IgG4-related sclerosing disease received 8 treatments of intravenously administered PEGylated liposomal methylprednisolone-succinate (NSSL-MPS). Due to the ethical requirements to reduce IRs, the patient received a cocktail of premedication including low dose of steroids, acetaminophen and H2 bloc ...[more]