Ontology highlight
ABSTRACT:
SUBMITTER: Saitoh Y
PROVIDER: S-EPMC7038917 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Saitoh Yuu Y Umezu Tomohiro T Imanishi Satoshi S Asano Michiyo M Yoshizawa Seiichiro S Katagiri Seiichiro S Suguro Tamiko T Fujimoto Hiroaki H Akahane Daigo D Kobayashi-Kawana Chiaki C Ohyashiki Junko H JH Ohyashiki Kazuma K
Oncology letters 20200109 3
To evaluate the mechanism underlying the communication between myeloid malignant and bone marrow (BM) microenvironment cells in disease progression, the current study established BM mesenchymal stromal cells (MSCs) and assessed extracellular vesicle (EV) microRNA (miR) expression in 22 patients with myelodysplastic syndrome (MDS) and 7 patients with acute myeloid leukemia and myelodysplasia-related changes (AML/MRC). Patients with MDS were separated into two categories based on the revised Inter ...[more]