Ontology highlight
ABSTRACT:
SUBMITTER: Murthy AC
PROVIDER: S-EPMC7039561 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Murthy Anastasia C AC Fawzi Nicolas L NL
The Journal of biological chemistry 20200107 8
Liquid-liquid phase separation (LLPS) of proteins and nucleic acids is a phenomenon that underlies membraneless compartmentalization of the cell. The underlying molecular interactions that underpin biomolecular LLPS have been of increased interest due to the importance of membraneless organelles in facilitating various biological processes and the disease association of several of the proteins that mediate LLPS. Proteins that are able to undergo LLPS often contain intrinsically disordered region ...[more]