Ontology highlight
ABSTRACT:
SUBMITTER: Starsta M
PROVIDER: S-EPMC7043789 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Stårsta Magnus M Hammarlöf Disa L DL Wäneskog Marcus M Schlegel Susan S Xu Feifei F Heden Gynnå Arvid A Borg Malin M Herschend Sten S Koskiniemi Sanna S
PLoS genetics 20200213 2
RHS elements are components of conserved toxin-delivery systems, wide-spread within the bacterial kingdom and some of the most positively selected genes known. However, very little is known about how Rhs toxins affect bacterial biology. Salmonella Typhimurium contains a full-length rhs gene and an adjacent orphan rhs gene, which lacks the conserved delivery part of the Rhs protein. Here we show that, in addition to the conventional delivery, Rhs toxin-antitoxin pairs encode for functional type-I ...[more]