Ontology highlight
ABSTRACT:
SUBMITTER: Taffoni C
PROVIDER: S-EPMC7043892 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Taffoni Clara C Omi Shizue S Huber Caroline C Mailfert Sébastien S Fallet Mathieu M Rupprecht Jean-François JF Ewbank Jonathan J JJ Pujol Nathalie N
eLife 20200129
The skin protects animals from infection and physical damage. In <i>Caenorhabditis elegans,</i> wounding the epidermis triggers an immune reaction and a repair response, but it is not clear how these are coordinated. Previous work implicated the microtubule cytoskeleton in the maintenance of epidermal integrity (Chuang et al., 2016). Here, by establishing a simple wounding system, we show that wounding provokes a reorganisation of plasma membrane subdomains. This is followed by recruitment of th ...[more]