Ontology highlight
ABSTRACT:
SUBMITTER: Fridman V
PROVIDER: S-EPMC2672901 | biostudies-other | 2009 Apr
REPOSITORIES: biostudies-other
Fridman Vladimir V Gerson-Gurwitz Adina A Movshovich Natalia N Kupiec Martin M Gheber Larisa L
EMBO reports 20090306 4
To study the dynamics of interpolar microtubules (iMTs) in Saccharomyces cerevisiae cells, we photobleached a considerable portion of the middle region of anaphase spindles in cells expressing tubulin-green fluorescent protein (GFP) and followed fluorescence recovery at the iMT plus-ends. We found that during anaphase, iMTs show phases of fast growth and shrinkage that are restricted to the iMT plus-ends. Our data indicate that iMT plus-end dynamics are regulated during mitosis, as fluorescence ...[more]