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MitoBlue as a tool to analyze the mitochondria-lysosome communication.


ABSTRACT: MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mitochondria and lysosomes.

SUBMITTER: Sanchez MI 

PROVIDER: S-EPMC7044336 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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MitoBlue as a tool to analyze the mitochondria-lysosome communication.

Sánchez Mateo I MI   Vida Yolanda Y   Pérez-Inestrosa Ezequiel E   Mascareñas José L JL   Vázquez M Eugenio ME   Sugiura Ayumu A   Martínez-Costas José J  

Scientific reports 20200226 1


MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mit  ...[more]

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