Ontology highlight
ABSTRACT:
SUBMITTER: Somu C
PROVIDER: S-EPMC7044713 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Somu Chaithanya C Mohan Chakrabhavi Dhananjaya CD Ambekar Sachin S Dukanya Rangappa Shobith S Baburajeev C P CP Sukhorukov Alexey A Mishra Srishti S Shanmugam Muthu K MK Chinnathambi Arunachalam A Awad Alahmadi Tahani T Alharbi Sulaiman Ali SA Basappa Rangappa Kanchugarakoppal S KS
Biotechnology reports (Amsterdam, Netherlands) 20200219
Constitutive activation of NF-κB is associated with proinflammatory diseases and suppression of the NF-κB signaling pathway has been considered as an effective therapeutic strategy in the treatment of various cancers including hepatocellular carcinoma (HCC). Herein, we report the synthesis of 1,2 oxazines and their anticancer potential. The antiproliferative studies presented 3-((4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)methyl)-4-phenyl-4,4a,5,6,7,7a-hexahydrocyclopenta [<i>e</i>][1,2]oxazine( ...[more]